Chinese scientists set up a faster and more efficient reprogramming system for human cytochemistry.

  Peking University Deng Hongkui’s research group recently published a research paper entitled "Efficient and Rapid Preparation of Human Pluripotent Stem Cells by Chemical Reprogramming" in the international academic journal Cell Stem Cells. In this study, a new chemical reprogramming system was established to induce human adult cells into pluripotent stem cells more quickly and efficiently.
  According to the team members, pluripotent stem cells have the ability of infinite self-renewal and differentiation into all functional cell types of organisms. These magical characteristics make them widely used in cell therapy, drug screening and disease models, and they are the most critical "seed cells" in the field of regenerative medicine. How to induce pluripotent stem cells in vitro has always been a key scientific problem in the field of life science. In 2013, Deng Hongkui’s research group published an original achievement in the journal Science, that is, it can reverse the fate of cells without relying on endogenous substances such as oocytes and transcription factors, and reprogram mouse somatic cells into pluripotent stem cells (CiPS cells), opening up a new path of somatic cell reprogramming. In 2022, Deng Hongkui’s research group made a new breakthrough and successfully realized the induction of human adult cells into pluripotent stem cells (human CiPS cells) by using small chemical molecules.
  The essence of life is a chemical process, and it is theoretically the most effective way to regulate the fate of cells through small chemical molecules. There are essential differences between chemical reprogramming and traditional reprogramming technology: traditional transgenic reprogramming technology, such as induced pluripotent stem cell technology (iPS technology), drives the cell fate to change directly through the over-expression of endogenous transcription factors, and its induction process is difficult to control; Chemical reprogramming is to use exogenous chemical small molecules to simulate external signal stimulation and drive the cell fate to change in stages. Therefore, this method has strong controllability, and it is expected to achieve precise regulation of cell fate, reverse cell identity and functional state, and make reverse development possible.
  In this latest research achievement, Deng Hongkui has established a faster, more efficient and more stable reprogramming method of human cytochemistry. The researchers discovered a new combination of small chemical molecules, which greatly accelerated the reprogramming process. The induction period was shortened from 50 days to less than 30 days, and the induction could be completed in 16 days at the shortest. At the same time, the induction efficiency is greatly improved, up to 31%. The new system was tested on somatic cells from 17 individuals with different genetic backgrounds and different ages, and all of them could be induced efficiently, which accelerated the wide application of human CiPS cells in cell therapy, drug screening and disease models.
  According to the previous report of the research group, the original system went through the stages of epithelioid cells, plastic intermediate cells and XEN-like cells in the process of inducing human CiPS cells, and finally established pluripotent stem cells. However, this study found that the molecular mechanism of the new system is faster and more efficient: the proliferation ability and oxidative phosphorylation metabolic activity of plastic intermediate cells are significantly enhanced, and they no longer go through XEN-like stage, and the pluripotent genes are activated faster and the molecular path is more direct. It is particularly important that traditional iPS reprogramming relies on the process of glycolysis and metabolism, while the most critical stage of chemical reprogramming-the production of plastic intermediate state depends on oxidative phosphorylation, not glycolysis and metabolism. This discovery reveals the importance of specific energy metabolism pathways to the fate transformation process of different cells, and provides a new perspective for understanding the regulation mechanism of cell fate from the perspective of energy metabolism.
  In addition, the new induction scheme established in this study is not only fast, efficient and stable, but more importantly, it has clear components, and does not depend on serum or feeder cells. These properties better meet the needs of clinical application, laying a foundation for establishing human CiPS cell lines that meet the clinical application standards and making it a key step towards clinical application. Compared with transgenic over-expressed transcription factors, chemical small molecules have the advantages of not integrating genome, reversible action and simple operation, so CiPS technology is safer, simpler and easier to standardize, and has broad clinical application prospects. At present, Deng Hongkui’s research group has efficiently prepared islet cells from human CiPS cells, and verified its safety and effectiveness in treating diabetes in large animal models, highlighting the clinical application value of human CiPS cells as "seed cells" in treating major diseases.
  

In the world box office, there are no China films on the list, and Avatar ranks first.

Recently, the list of 52 films with the highest box office in the world in the 44 years since 1977 was released. The number one movie was Avatar in 2009, and the global box office reached an astonishing $2,922,917,914. This was followed by The Avengers: The Final Battle in 2019, with a box office of $2,797,501,328. Both films have grossed more than $2 billion.

Other popular movies on the list include Titanic (1997, global box office: US$ 2,201,647,264), Star Wars: The Force Awakens (2015, global box office: US$ 2,069,521,700) and The Avengers: Infinite War (2018, global box office) In the China market, so far, no film has been selected for this list.

In addition, Avatar: The Way of Water in 2022 and Spider-Man: No Way Out in 2021 also ranked 6th and 7th respectively, with global box office of $2,026,675,670 and $1,916,306,995 respectively.

In this list, the tenth film is The Avengers in 2012, with a global box office of $1,518,815,515; The seventh place was Fast and furious 7 in 2015, with a global box office of $1,515,341,399. Other famous films such as The Lion King (2019, global box office: US$ 1,663,075,401) and Top Gun: maverick (2022, global box office: US$ 1,488,732,821) are also on the list.

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In 2019, the list of the top 100 private enterprises in Beijing released four lists.

China Net Beijing November 15 th This morning, the Beijing Federation of Industry and Commerce released the list of "Top 100 Private Enterprises in Beijing in 2019", "Top 100 Scientific and Technological Innovations of Private Enterprises in Beijing in 2019", "Top 100 Cultural Industries of Private Enterprises in Beijing in 2019" and "Top 100 Social Responsibility of Private Enterprises in Beijing in 2019".

The full list is as follows:


List of Top 100 Private Enterprises in Beijing in 2019

1.JD.COM Group

2. Legend Holdings Limited by Share Ltd

3. Gome Holding Group Co., Ltd

4. Xiaomi Communication Technology Co., Ltd.

5. Taikang Insurance Group Limited by Share Ltd.

6. Beijing Jianlong Heavy Industry Group Co., Ltd

7. Baidu Company

8. Beijing Sankuai Technology Co., Ltd.

9. Tianan Life Insurance Company Limited

10. Wumart Technology Group Co., Ltd.

11. Beijing Yuntong Guorong Investment Group Co., Ltd

12. Ruiganglian Group Co., Ltd.

13. Dihai Investment Holding Group Co., Ltd.

14. Dickson Technology Group Co., Ltd.

15. Beijing Lianjia Real Estate Agency Co., Ltd.

16. Beijing Suning.cn Sales Co., Ltd.

17 Beijing Blue Cursor Data Technology Co., Ltd.

18. Dongzhao Changtai Group Limited

19. Beijing iQiyi Technology Co., Ltd.

20. Beijing Dabei Agricultural Technology Group Co., Ltd.

21. Beijing Silian Venture Chemical Group Co., Ltd.

22. Beijing Xuesisi Education Technology Co., Ltd.

23. Jianghe Creation Group Co., Ltd.

24 Minsheng Life Insurance Co., Ltd.

25. WANDA CINEMAS Limited by Share Ltd.

26. Beijing Oriental Yuhong Waterproof Technology Co., Ltd.

27. Digital China Software Co. Ltd.

28 China Qinghua Energy Group Co., Ltd.

29. Zhongxin Tourism Group Co., Ltd.

30 Beijing Liandong Investment (Group) Co., Ltd.

31 Beijing Bishuiyuan Technology Co., Ltd.

32 Beijing Dangdang Information Technology Co., Ltd.

33 Huayang Lianzhong Digital Technology Co., Ltd.

34. Beijing Tomorrow Investment Co., Ltd

35 Beijing Yonghui Supermarket Co., Ltd.

36 Beijing Weimeng Chuangke Network Technology Co., Ltd.

37. Beijing Tasly Medicine Co., Ltd.

38 Beijing Juncheng Industry Investment Group Co., Ltd.

39. Donghua Software Co., Ltd

40 Beijing Hongkun Weiye Real Estate Development Co., Ltd.

41. Origen Technology Co., Ltd.

42. iSoftStone Information Technology (Group) Co., Ltd.

43. Contemporary Energy Saving Real Estate Co., Ltd.

44 UFIDA Network Technology Co., Ltd.

45. Liard Optoelectronics Co., Ltd.

Lacarra Group.

47. Sany Heavy Industry Company Limited

48. Hongkang Life Insurance Company Limited

49 Beijing Zhongneng Haolong Investment Holding Group Co., Ltd.

50. Beijing Qianfang Technology Co., Ltd.

51. Beijing SF Express Co., Ltd

52. Lepu (Beijing) Medical Devices Co., Ltd.

53. Beijing Zhonggong Education Technology Co., Ltd.

54. Beijing Fangshan Yandong Chemical Plant

55. Beijing Guanghuan New Network Technology Co., Ltd.

56 Beijing Caesar International Travel Service Co., Ltd.

57 Beijing Jiuzhoutong Pharmaceutical Co., Ltd.

58. Beijing Natong Technology Group Co., Ltd.

59. Beijing Digital Technology Co., Ltd.

60 Beijing Huasheng Tiancheng Technology Co., Ltd.

61. Guojin Gold Company Limited

62. Beijing Jinfeng Kechuang Wind Power Equipment Co., Ltd.

63. Beijing Cheetah Mobile Technology Co., Ltd.

64 Beijing Heng Chang Litong Investment Management Co., Ltd.

65. Beijing Huaxia Jianlong Mining Technology Co., Ltd.

66. Botian Environment Group Co., Ltd

67. Beijing Jiayu Door and Window Curtain Wall Co., Ltd.

68 Jiayou International Logistics Co., Ltd.

69 Beijing Changyou Times Digital Technology Co., Ltd.

70 Beijing Pinzhong Interactive Network Marketing Technology Co., Ltd.

71. Beijing Milaiwu Network Technology Co., Ltd.

72. Ruihua Group

73. Beijing High Energy Times Environmental Technology Co., Ltd.

74. Beijing Sinosteel Information Co., Ltd.

75 Beijing Sanrenxing Digital Communication Co., Ltd.

76. Beijing Kuncang Wanwei Technology Co., Ltd.

77. Beijing Xinfangsheng Hardware & Electric Material Co., Ltd.

78 AsiaInfo Technology (China) Co., Ltd.

79. Daheng New Era Technology Co., Ltd

80. Beijing May 8th Information Technology Co., Ltd.

81 Beijing Jialin Pharmaceutical Co., Ltd.

82. Beijing Qiyuan Technology Co., Ltd.

83. Dongxu Technology Group Co., Ltd.

84 Jin Chengxin Mining Management Co., Ltd.

85 Beijing Changjiu Logistics Co., Ltd.

86. Beijing Wanxing Construction Group Co., Ltd.

87. Beijing Shengshi Xinxing Gree Trading Co., Ltd.

88 Beijing Tiancheng Tongchuang Electric Co., Ltd.

89. Centro Shixing Group Limited by Share Ltd.

90 Beijing Weichuang Times Advertising Co., Ltd.

91. Hollysys Technology Group Limited

92. Beijing Oriental Huibo Human Resources Consultant Co., Ltd.

93. Guanglianda Technology Co., Ltd.

94. Qumei Home Group Co., Ltd.

95. Boyan Technology Co., Ltd.

96. Beijing Hengan Guardian Security Service Co., Ltd.

97 Beijing Stone Century Technology Co., Ltd.

98 Beijing Rongzhilian Technology Co., Ltd.

99. Pay with You Limited

100. Competitive World (Beijing) Network Technology Co., Ltd.

List of Top 100 Scientific and Technological Innovations of Private Enterprises in Beijing in 2019

1. Baidu Company

2. Beijing Changyou Times Digital Technology Co., Ltd.

3. Beijing Sankuai Online Technology Co., Ltd.

4. Digital China Software Co., Ltd.

5. Qi Anxin Technology Group Co., Ltd.

6. JD.COM Group

7. UFIDA Network Technology Co., Ltd.

8. Guanglianda Technology Co., Ltd.

9. Xiaomi Communication Technology Co., Ltd.

10. Beijing Calorie Information Technology Co., Ltd.

11. Beijing Xuesisi Education Technology Co., Ltd.

12. Venus Information Technology Group Co., Ltd.

13. Beijing Defiance Technology Co., Ltd

14. ICT Group Limited

15. Competitive World (Beijing) Network Technology Co., Ltd.

16 Beijing Kunlun Wanwei Technology Co., Ltd.

17. Beijing Hezhong Sizhuang Technology Co., Ltd.

18. Dongfang Netpower Technology Co., Ltd.

19. Ruikangda Technology Development Co., Ltd.

20. Beijing Diandi Intelligent Technology Co., Ltd.

21. Beijing Geling Shentong Information Technology Co., Ltd.

22. Beijing Shiqiao Biopharmaceutical Co., Ltd.

23. Fengke Find a House (Beijing) Technology Co., Ltd.

24. Lepu (Beijing) Medical Devices Co., Ltd.

25. Beijing Dream World Technology Co., Ltd.

26. Online Tour (Beijing) Technology Co., Ltd.

27. Beijing Jinfeng Kechuang Wind Power Equipment Co., Ltd.

28. AsiaInfo Technology (China) Co., Ltd.

29. Beijing Zhongke Jincai Technology Co., Ltd.

30. Hollysys Technology Group Limited

31. Donghua Software Co., Ltd

32 Beijing Suntech Online Education Technology Co., Ltd.

33 Beijing Dongtu Technology Co., Ltd.

34. Beijing Lange Electronic Commerce Co., Ltd.

35. Ai Qianjin (Beijing) Information Technology Co., Ltd.

36 Beijing Yuxin Technology Group Co., Ltd.

Lacarra Group.

38. Beijing Xinlei Energy Technology Co., Ltd.

39. Cross-border Cloud (Beijing) Network Technology Co., Ltd.

40. Beijing Bank-Enterprise Integration Technology Development Co., Ltd.

41. Beijing Fanzizi Gene Technology Co., Ltd.

42 Beijing Rongzhilian Technology Co., Ltd.

43. Blueport Online (Beijing) Technology Co., Ltd.

44. Beijing Milaiwu Network Technology Co., Ltd.

45. Vision Power Information Technology Co., Ltd.

46 Beijing Minhai Biotechnology Co., Ltd.

47. Liard Optoelectronics Co., Ltd.

48. Shutaishen (Beijing) Biopharmaceutical Co., Ltd.

49 Beijing Dabei Agricultural Science and Technology Group Co., Ltd.

50. Beijing Lianjia Real Estate Agency Co., Ltd.

51. Jianghe Creation Group Co., Ltd.

52. Beijing Zhifei Green Bamboo Biopharmaceutical Co., Ltd.

53 Yingu Pharmaceutical Co., Ltd.

54 Beijing Jiaxun Feihong Electric Co., Ltd.

55. Beijing Const Instrument Technology Co., Ltd.

56 Beijing Jinyunshan Network Technology Co., Ltd.

57. Daheng New Era Technology Co., Ltd.

58 Beijing Jianlong Heavy Industry Group Co., Ltd.

59. Beijing Fuyuan Pharmaceutical Co., Ltd.

60. Beijing Shuangqi Century Technology Co., Ltd.

61. Beijing Greenweidi Technology Co., Ltd.

62. Boyan Technology Co., Ltd.

63. Beijing Digital Technology Co., Ltd.

64. Beijing Digital Video Software Technology Development Co., Ltd.

65 Beijing Tiancheng Tongchuang Electric Co., Ltd.

66 Beijing Natong Technology Group Co., Ltd.

67. Ganli Pharmaceutical Co., Ltd

68. Beijing High Energy Times Environmental Technology Co., Ltd.

69 Beijing Yiqiao Shenzhou Technology Co., Ltd.

70. Alte Automotive Technology Co., Ltd.

71. Zhangyue Technology Co., Ltd

72. Beijing Jinhe Network Co., Ltd

73. Beijing Wan Tai Biopharmaceutical Co., Ltd.

74 Beijing Hehe Medical Diagnostic Technology Co., Ltd.

75 Beijing Kangchen Pharmaceutical Co., Ltd.

76 Huayang Lianzhong Digital Technology Co., Ltd.

77. Beijing Golden Nonghua Seed Industry Technology Co., Ltd.

78 Beijing Aidite Information Technology Co., Ltd.

79 Beijing Oriental Guoxin Technology Co., Ltd.

80 Beijing Bishuiyuan Technology Co., Ltd.

81. Beijing Shengborun High-tech Co., Ltd.

82 Beijing berry and kang Biotechnology Co., Ltd.

83 Beijing Digital Video Payment Technology Co., Ltd.

84. Beijing Power Source Technology Co., Ltd.

85 Beijing Pinchi Medical Equipment Co., Ltd.

86. Beijing Yonghang Technology Co., Ltd.

87 Beijing Jietai Tianyu Information Technology Co., Ltd.

88 Beijing huijin technology Co., Ltd.

89. Interstellar Entertainment (Beijing) Technology Co., Ltd.

90. Beijing Xinghao Pharmaceutical Co., Ltd.

91. Beijing Guanghuan New Network Technology Co., Ltd.

92. Beijing Tianshen Interactive Technology Co., Ltd.

93. Beijing North Information Technology Co., Ltd.

94. Beijing Lideheng Environmental Engineering Co., Ltd.

95. Beijing Fangsheng Industry Co., Ltd

96. Tianmai Juyuan (Beijing) Technology Co., Ltd.

97. Beijing Xuedilong Technology Co., Ltd.

98. Beijing Oriental Yuhong Waterproof Technology Co., Ltd.

99 Beijing Yixin Yixing Automobile Technology Development Service Co., Ltd.

100 Beijing Liuhe Weiye Technology Co., Ltd.

2019 Top 100 Cultural Industries of Private Enterprises in Beijing

1. Xiaomi Communication Technology Co., Ltd.

2. Baidu Company

3. Beijing Xueersi Education Technology Co., Ltd

4. First Momo Asset Management (Beijing) Co., Ltd.

5. Beijing Blue Cursor Data Technology Co., Ltd

6. Dihai Investment Holding Group Co., Ltd.

7. UFIDA Network Technology Co., Ltd.

8. Beijing iQiyi Technology Co., Ltd.

9. Digital China Software Co., Ltd.

10. Vision Power Information Technology Co., Ltd.

11. WANDA CINEMAS Limited by Share Ltd.

12. Beijing Qianfang Technology Co., Ltd.

13 Beijing Changyou Times Digital Technology Co., Ltd.

14. Dickson Technology Group Co., Ltd.

15. Zhongxin Tourism Group Co., Ltd

16. Beijing Jinshan Cloud Network Technology Co., Ltd.

17. Guojin Gold Company Limited

18. Beijing Dangdang Information Technology Co., Ltd.

19. Beijing Digital Technology Co., Ltd.

20. Donghua Software Co., Ltd

21. Beijing Kuncang Wanwei Technology Co., Ltd.

22. Beijing Weimeng Chuangke Network Technology Co., Ltd

23. iSoftStone Information Technology (Group) Co., Ltd.

24. Beijing Huasheng Tiancheng Technology Co., Ltd.

25. Beijing Guanghuan New Network Technology Co., Ltd.

26. Beijing Zhonggong Education Technology Co., Ltd.

27. Daheng New Era Technology Co., Ltd.

28 Beijing Caesar International Travel Service Co., Ltd.

29. Beijing Cheetah Mobile Technology Co., Ltd.

30. Dongfang Netpower Technology Co., Ltd.

31 Beijing Heng Chang Litong Investment Management Co., Ltd.

32 Beijing Rongzhilian Technology Co., Ltd.

33. Beijing Sinosteel Information Co., Ltd.

34. Ruikangda Technology Development Co., Ltd.

35. Beijing Yonghang Technology Co., Ltd.

36 AsiaInfo Technology (China) Co., Ltd.

37 Beijing Sanrenxing Digital Communication Co., Ltd.

38. Beijing Milewood Network Technology Co., Ltd.

39. Beijing Zhongke Jincai Technology Co., Ltd.

40. Beijing Chinese and Foreign Celebrity Culture Technology Co., Ltd.

41 Beijing Pinzhong Interactive Network Marketing Technology Co., Ltd.

42. China Television Telegraphic Media Co., Ltd.

43. Zhangyue Technology Co., Ltd.

44 Beijing Oriental Guoxin Technology Co., Ltd.

45. Beijing Qiyuan Technology Co., Ltd.

46. Guanglianda Technology Co., Ltd

47. Beijing May 8th Information Technology Co., Ltd.

48. Boyan Technology Co., Ltd.

49. Venus Information Technology Group Co., Ltd.

50. Competitive World (Beijing) Network Technology Co., Ltd.

51. Beijing chiba jewelry Company Limited by Share Ltd.

52 Beijing Weichuang Times Advertising Co., Ltd.

53. Beijing CLP Xingfa Technology Co., Ltd.

54. yeepay Limited.

55. Beijing Wojie Culture Media Co., Ltd.

56. Beijing Oriental Huibo Human Resources Consultant Co., Ltd.

57 Beijing Heng Chang Huicai Investment Management Co., Ltd.

58 Beijing Huatu Hongyang Education and Culture Development Co., Ltd.

59 Beijing Sida Times Software Technology Co., Ltd.

60. Beijing Wangyi Media Co., Ltd.

61. Beijing Yuxin Technology Group Co., Ltd.

62. Le Element Technology (Beijing) Co., Ltd.

63. Beijing Star Network Ruijie Network Technology Co., Ltd.

64. Beijing Shenzhou Xinqiao Technology Co., Ltd.

65. Perfect World (Beijing) Software Technology Development Co., Ltd.

66 Beijing Shengtong Printing Co., Ltd.

67 Beijing Sina Internet Information Service Co., Ltd.

68 Beijing Jishi Interactive Network Marketing Technology Co., Ltd.

69 Beijing Suntech Online Education Technology Co., Ltd.

70. Beijing Shanhai Tourism Co., Ltd.

71. Beijing Times Guangying Culture Media Co., Ltd.

72 Beijing Heng Chang Huicheng Information Consulting Co., Ltd.

73 Beijing Chunqiu Yongle Culture Communication Co., Ltd.

74 Beijing Yougou Culture Development Co., Ltd.

75. Beijing Guodu Internet Technology Co., Ltd.

76 Beijing Jiaxun Feihong Electric Co., Ltd.

77 Beijing Yadea Media Co., Ltd.

78 Beijing teng letter Innovation Network Marketing Technology Co., Ltd.

79. Beijing Lange Electronic Commerce Co., Ltd.

80 Beijing Wentou Hangmei Media Co., Ltd.

81. Oriental Fashion Driving School Co., Ltd.

82. Beijing North Information Technology Co., Ltd.

83 Beijing Zifeng Culture Development Co., Ltd.

84 Beijing Kaisheng Culture Media Co., Ltd.

85 Beijing Yachang Art Printing Co., Ltd.

86. Star Entertainment (Beijing) Technology Co., Ltd.

87 Beijing Rentian Bookstore Co., Ltd.

88 Beijing Wuzhouxing International Travel Service Co., Ltd.

89. Beijing Times Lingzi Technology Co., Ltd.

90 Beijing Youbao Online Technology Co., Ltd.

91. Beijing Fengshang Century Culture Media Co., Ltd.

92. Jingyi Jinye Co., Ltd.

93. Zhongxin Sunac Capital Management Co., Ltd.

94 Beijing Guanglian Pioneer Network Technology Co., Ltd.

95 Chinese Online Digital Publishing Group Co., Ltd.

96 Beijing Jiuhe Interactive Cultural Communication Co., Ltd.

97. Ai Qianjin (Beijing) Information Technology Co., Ltd.

98. Beijing Yingkang Technology Co., Ltd.

99. Tianmai Juyuan (Beijing) Technology Co., Ltd.

100. Online Tour (Beijing) Technology Co., Ltd.

2019 Top 100 List of Social Responsibility of Private Enterprises in Beijing

1. Beijing High Energy Times Environmental Technology Co., Ltd.

2. Qi Anxin Technology Group Co., Ltd.

3. Oriental Fashion Driving School Co., Ltd.

4. Lepu (Beijing) Medical Devices Co., Ltd.

5. Beijing Natong Technology Group Co., Ltd.

6. Beijing Ainong Pension Service Co., Ltd.

7. Beijing Lange Electronic Commerce Co., Ltd.

8. Donghua Software Co., Ltd

9. Beijing Golden Nonghua Seed Industry Technology Co., Ltd.

10. Beijing Yimeng Tiandi Information Technology Co., Ltd

11. Sany Heavy Industry Company Limited

12. Lacarra Group

13 Beijing Xinfadi Agricultural and Sideline Products Wholesale Market Center

14. Beijing Kexin Printing Co., Ltd

15. Beijing Chunlingda Medical Devices Co., Ltd.

16. Perfect World (Beijing) Software Technology Development Co., Ltd.

17 Beijing Blue Cursor Data Technology Co., Ltd.

18. Beijing Aoteshur Health Products Development Co., Ltd.

19. Beijing Shanhai Tourism Co., Ltd.

20. Beijing Times Ling Yu Technology Co., Ltd.

21 Beijing Jiaxun Feihong Electric Co., Ltd.

22 Beijing Fazheng Industrial Group Co., Ltd.

23. Beijing Lideheng Environmental Engineering Co., Ltd.

24. Beijing Daxing Fa Trading Co., Ltd.

25. Xiaomi Communication Technology Co., Ltd.

26. Beijing Yachang Art Printing Drama Co., Ltd.

27. Qianyida Group Co., Ltd

JD.COM Group

29. Fanhua Construction Group Co., Ltd.

30 Beijing Fule Technology Development Co., Ltd.

31. Beijing Lianjia Real Estate Agency Co., Ltd.

32. Beijing Yuanliu Hongyuan Electronic Technology Co., Ltd.

33. Beijing Sanfu Outdoor Products Co., Ltd.

34 Beijing Hanguang Department Store Co., Ltd.

35. 91 Pioneer Technology Group Co., Ltd.

36. KPMG Huazhen Certified Public Accountants (special general partnership)

37 Beijing Tianheng Construction Group Co., Ltd.

38 Beijing Huabo Chuangke Technology Co., Ltd.

39 Beijing Sankuai Online Technology Co., Ltd.

40. Beijing Milewood Network Technology Co., Ltd.

41. Beijing Weishiyuan Food Technology Co., Ltd.

42 Beijing Changjiu Logistics Co., Ltd.

43 Beijing Kangrentang Pharmaceutical Co., Ltd.

44. Beijing May 8th Information Technology Co., Ltd.

45. Xihua Industrial Investment Group Co., Ltd.

46. Beijing SF Express Co., Ltd

47 Beijing Heng Chang Litong Investment Management Co., Ltd.

48. Beijing Hezhong Sizhuang Technology Co., Ltd.

49. Beijing Xinmin Heng Automobile Sales Co., Ltd.

50 Minsheng Life Insurance Co., Ltd.

51. Beijing Jintongyuan Construction Engineering Company

52. Lowa Technology Industry Group Co., Ltd.

53. Beijing Hongyuan Nanmen Hotpot City Co., Ltd.

54. Beijing Minhai Biotechnology Co., Ltd

55 Beijing Jialin Pharmaceutical Co., Ltd.

56 Beijing PetroChina Fangshan Yanbin Oil Sales Co., Ltd.

57. Beijing Green Sea Technology Co., Ltd.

58 Beijing Xingpai Sporting Goods Group Co., Ltd.

59. Beijing Tengxin Technology Co., Ltd

60. Zhongke Yutu Technology Co., Ltd

61. Beijing Kaida Hengye Agricultural Technology Development Co., Ltd.

62. Ai Qianjin (Beijing) Information Technology Co., Ltd.

63. Beijing Life Insurance Company Limited

64. Origen Technology Co., Ltd.

65 Beijing Kang Bei Ni Food Co., Ltd.

66 Beijing Great Wall Guard Security Co., Ltd.

67. Beijing Wanxing Construction Group Co., Ltd.

68 Beijing Ketaixingda High-tech Co., Ltd.

69. Rongweiyuan Security Service (Beijing) Co., Ltd.

70. Beijing Oriental Jiacheng Cultural Industry Development Co., Ltd.

71. Liard Optoelectronics Co., Ltd.

72. UFIDA Network Technology Co., Ltd.

73 Beijing Bishuiyuan Technology Co., Ltd.

74 Jimei Holding Group Co., Ltd.

75. Boyan Technology Co., Ltd.

76. Tianan Life Insurance Company Limited

77. Qingjingyuan (Beijing) Environmental Protection Technology Co., Ltd.

78 Chinese Online Digital Publishing Group Co., Ltd.

79 Taikang Insurance Group Co., Ltd.

80. Beijing Oriental Huibo Human Resources Consultant Co., Ltd.

81 Pathfinder Holding Group Co., Ltd.

82. Beijing Huajiang Culture Group Co., Ltd

83. Guojin Gold Company Limited

84. Beijing Kangzhu Medical Equipment Co., Ltd.

85 Beijing Jingdiao Technology Group Co., Ltd.

86. Tianjian Engineering Consulting Co. Ltd.

87. Beijing Sinosteel Information Co., Ltd.

88. Contemporary Energy Saving Real Estate Co., Ltd.

89 Beijing Shangtang Printing and Packaging Co., Ltd.

90. Digital China Software Co. Ltd.

91. Centro Shixing Group Limited by Share Ltd.

92. Qumei Home Group Co., Ltd.

93 Beijing Xueersi Education Technology Co., Ltd.

94 Beijing Kangchen Pharmaceutical Co., Ltd.

95. Beijing Tiangang Additives Co., Ltd.

96 Beijing Kaiser International Travel Service Co., Ltd.

97 Zhongke Hengyuan Technology Co., Ltd.

98 Beijing Lianfeixiang Technology Co., Ltd.

99. Beijing Shangkun Education Holding Group Co., Ltd.

100 Venus Information Technology Group Co., Ltd.

Related links:

       In 2019, the list of the top 100 private enterprises in Beijing was released, and the overall strength of the top 100 private enterprises increased

       2019 Beijing Top 100 Private Enterprises Announced JD.COM Lenovo Gome won the top three.

      

How to renovate the film marketing at present, starting from the screening ceremony of Meng Hua Lu.


Special feature of 1905 film network Recently, with the gradual improvement of the epidemic situation, cinemas have also ushered in a new "restart". The online drama market, which has not been affected by the epidemic before, has produced many excellent works. Meng Hua Lu, which detonated the whole network this summer, also ushered in a grand finale.

Since its launch, this drama has won the hearts of many audiences. The live screening ceremony of the finale of Dream of China was held on June 26th, and the total number of reservations was close to 800,000, which was both eye-catching and golden.



The novel marketing method of the live broadcast ceremony of the finale of Meng Hua Lu has also made many netizens see the marketing potential of film and television works. Especially in the post-epidemic era, how to renovate film marketing has become a topic worthy of discussion. In this issue, Weng Yang, an associate professor at the School of Management of Beijing Film Academy, was invited to talk about film marketing with you.



The finale screening ceremony of Meng Hua Lu invited the main stars of the series to broadcast live together and enjoy the finale with the audience who followed the drama for a long time. This screening ceremony not only gave many viewers a sense of freshness, but also caused some controversy.

Some netizens think that this practice is an advanced screening in disguise. Weng Yun agrees with this view: "Let’s go back to its essence, or simply package our star, which is the marketing element, with this sales action that its own platform may want to do, but it skillfully borrows a marketing concept, that is, the concept of premiere, which is very common in film projects."



Many viewers believe that the emotional value brought by watching the drama with their favorite stars is far more worthwhile than watching the finale itself in advance. This just proves that as long as the audience’s choice is respected, the audience will also recognize it. At the same time, this relatively successful marketing case also gives a reference to the filmmakers in the post-epidemic era. No matter from strength or pattern, film marketing is often richer than drama marketing. From the observation, there are some new trends in film marketing in recent years.



First of all, the participation of stars in the live broadcast has become one of the popular marketing methods. Weng Yun shared an example. At the time of release, the marketing party designed to let the director walk into the live broadcast room and talk with six vertical talents. With the accumulated spread of these talents, more non-core circle users will also come into contact with the film. Judging from the data performance of the live broadcast, it is also very eye-catching.



With the popularity of short videos, marketing through short videos has become a popular way. Because of the characteristics of short, flat and fast, short video marketing often leaves few memory points for the audience, so the development of short video marketing has also reached a bottleneck, but some content through short video marketing will also arouse the interest of the audience, such as the file scheduled for next year’s Spring Festival, in this year’s Spring Festival file, short video materials have been released, and the content is to celebrate the New Year for everyone. Short video marketing also shows the trend of film marketing action leading.



In addition, the movie cloud premiere is also a relatively new and popular marketing tool. At present, this method is also adopted in the release, starring and interacting with the audience through cloud connection after the film is shown. The whole cloud premiere is rich in topics and the communication effect is also very good.



Judging from these popular marketing methods in recent years, many films actively adopt online marketing methods. For example, the starring actor mentioned in an interview that "all aspects of the new stage should adapt to new ways". In this post-epidemic era, film marketers need to make more explorations to maintain the audience’s enthusiasm for movies.



We can foresee that the film marketing in the post-epidemic era will be more interactive. When watching movies, many viewers will have a strong desire to share, and they will want to interact with the film through some online or offline ways. They can remind the audience to punch in as a souvenir through some special video materials, or bury some stalks that can interact with the audience in the film.

This method can achieve an interactive marketing closed loop online and offline through a low budget. If the number of the leading actor "San Ge" is published in the hit movie, you can add him as a WeChat friend and check his circle of friends to see the eggs outside the movie.



Cross-border cooperation is also the direction that film marketing can explore, and additional marketing effects can be achieved through the development of derivatives. In addition, with the rapid development of science and technology, the possibility of film marketing is quite rich through the empowerment of science and technology. Weng Yun wondered: "In the future, whether we can use holographic projection to interact with us more in this way when doing various activities, which I think are actually better things to see."



At the moment when cinemas are gradually recovering from the epidemic, we hope to see popular works with a big reputation to ignite the whole film market. I also hope to see more interesting film marketing to attract the audience into the cinema. Of course, marketing is icing on the cake, and what really plays a practical role is still the quality of the film itself. It is expected that in the second half of 2022, we can witness the China movies coming out of their own bright future.


How awesome is Wuhan Virus Research Institute?

  On December 8, 2017, Fu Cong, head of the China delegation, said at the meeting of States parties to the United Nations Biological Weapons Convention that in October of that year, Wuhan Institute of Virology, Chinese Academy of Sciences held the International Training Course on Biosafety Laboratory Management and Experimental Technology.

  Don’t underestimate this conference, which is the most important achievement of China virus research in the world. The trainees of this training course organized by Wuhan Virus came from Pakistan, Kazakhstan, Sri Lanka, Egypt, Kenya, Serbia, Hungary and other countries. At that time, the lecture team of the training course came from the P4 laboratory construction and research team of Wuhan Institute of Virology. This laboratory has the highest level of protection in China and even in Asia, except for China, the other one is in Japan. At the end of December last year, at the beginning of the discovery of Covid-19, the relevant samples were directly sent to Wuhan P4 laboratory for testing. Later, relevant departments and institutions took the test results and published a paper entitled "Initial Transmission Dynamics of novel coronavirus-infected Pneumonia in Wuhan, China" in the New England Journal on January 29th. One of the conclusions was that "interpersonal transmission occurred among close contacts in December 2019". Recently, this paper has been questioned. The Ministry of Science and Technology recently issued a notice asking all relevant research project undertakers and their researchers to devote all their research energy to various research tasks, write the paper on the front line of fighting the epidemic, and apply the research results to fighting the epidemic. Before the task of epidemic prevention and control is completed, we should not focus on publishing the paper. In addition to the early discovery of human-to-human transmission in Covid-19, on January 28, the institute just developed an antibody detection test paper for research; At the same time, the Institute and the Institute of Toxicology and Drug Research of the Academy of Military Medical Sciences jointly discovered novel coronavirus (2019-nCoV) at the cellular level.Drugs with good inhibitory effects, such as remidivivir or rendixivir (GS-5734), chloroquine (Sigma-C6628), Ritonavir, etc. In addition, on January 21st, the Science and Technology Department of Hubei Province launched the "2019 New Type Pneumonia Emergency Science and Technology Research Project", and established a new type pneumonia emergency science and technology research expert group, whose leader is Shi Zhengli, a researcher at Wuhan Institute of Virology.

  In addition, the whole genome sequence of novel coronavirus was determined by Wuhan Institute of Virology on January 2nd, and the virus strain was successfully isolated on January 5th. On January 9th, the virus strain resource has been put into the national virus resource database according to the standard, and has been preserved in a standardized way.

  Wuhan Institute of Virology was also the first institution to conclude that the virus strain originated from bats. On January 23rd, Shi Zhengli’s team published "The Discovery of a novel coronavirus and Its Possible Origin of Bats" on the pre-printed platform of bioRxiv, and proposed that a new type of pneumonia virus might originate from bats. It was confirmed for the first time that novel coronavirus used the same cells as SARS coronavirus to enter the receptor, and it was found that the sequence consistency between novel coronavirus and a bat coronavirus was as high as 96%. Born in 1956, the current director is a post-80s Wuhan Virus Institute, which has a long history and a high level, and is a department-level unit. In June 1956, shortly after the founding of New China, the famous virologist Academician Gao Shangyin, the famous microbiologist Academician Chen Huagui and Professor Jane Haoran and other scientists of the older generation established Wuhan Institute of Virology, which was one of the national institutes established earlier in China. Wuhan Institute of Virology is one of the first enrollment units with the right to confer degrees since the country resumed graduate enrollment. Up to now, the discipline has trained 429 master students and 174 doctoral students. At present, the discipline has 27 discipline groups with different professional directions, 30 doctoral tutors, 10 master tutors, including 3 Jie Qing and 10 people in the Hundred Talents Program. There are 240 graduate students, including 110 doctoral students. The China Virus Resource and Information Center under the Wuhan Virus Institute has the largest virus repository in Asia, and established the only China Virus Collection in China. The research direction of Wuhan virus is all important human viruses.Such as HIV, HCV, influenza virus, human cytomegalovirus (HCMV), tumor virus KSHV, herpes simplex virus (HSV), etc.) and new viruses of animal origin (such as SARS-CoV, avian influenza virus, arbovirus, etc.). Chen Xinwen, former director of Wuhan Institute of Virology, received his doctorate in virology from Wageningen University in the Netherlands in 2001. He has been engaged in cooperative research in American University of California, Berkley and German University of Duisburg-Essen. Chen Xinwen is also a winner of the Hundred Talents Program of Chinese Academy of Sciences and the National Outstanding Youth Fund. He has won the second prize of national technological invention and the second prize of Hubei Natural Science. He is currently the president of Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences. Chen Xinwen was succeeded by Wang Yanyi, who became the director of Wuhan Virus Institute in October 2018. Wang Yanyi is a female "post-80 s" scientific research cadre, and previously served as the deputy director of Wuhan Virus Research Institute.

  According to public information, Wang Yanyi was born in 1981. She graduated from Peking University College of Life Sciences in 2004, and then went to the University of Colorado to get a master’s degree. When she came to Wuhan University, she served as a lecturer and associate professor in the School of Life Sciences of Wuhan University for six years, during which she received her doctorate.

  In March 2012, Wang Yanyi was transferred to Wuhan Institute of Virology, Chinese Academy of Sciences. He served as the head of molecular immunology discipline and deputy director of the Center for Viral Pathology. In December 2014, he served as assistant to the director, and one year later he was promoted to deputy director of Wuhan Institute of Virology. Wang Yanyi’s main research direction is the interaction mechanism between virus and host. He has presided over or undertaken many projects such as National Natural Science Foundation and 973 Project. Published nearly 30 SCI papers in internationally renowned journals. In 2013, Wang Yanyi was selected as the first batch of top-notch young talents in the national "Ten Thousand Talents Program". Shi Zhengli, a "batwoman", was able to quickly find the virus or its source from bats after searching for the virus host for 13 years in COVID-19, which has a lot to do with one person and her team. This person is Shi Zhengli.

  Shi Zhengli’s team is working in the field.

  Shi Zhengli, known as "batwoman", has been engaged in the etiology research of new viruses for a long time, especially in the research on the traceability of SARS virus, and her leading team confirmed that bats are the natural hosts of SARS coronavirus. Since the outbreak of SARS virus 18 years ago, a large number of coronaviruses (SARSr-CoV) associated with severe acute respiratory syndrome have been found in bats, their natural hosts. At the beginning of this outbreak in Wuhan, Shi Zhengli’s team obtained full-length genome sequences from five patients, which are almost identical to each other and have a similarity of 79.5% with the genome sequence of SARS-CoV. Later, researchers further found that novel coronavirus (nCoV-2019) had 96% homology with Bat Coronavirus at the whole genome level. By analyzing the paired protein sequences of seven conserved nonstructural proteins, it was shown that novel coronavirus belonged to SARSr-CoV species. The team led by Shi Zhengli not only confirmed that bats are the natural hosts of SARS coronavirus, but also found serological evidence that bats in China are infected with Nipah virus and Ebola virus, and found and identified a large number of genetically diverse new viruses such as adenovirus and circovirus in bats, further confirming that bats are the natural hosts of many viruses. Before and after the Spring Festival in 2003, SARS spread from Guangdong Province to other provinces in China at an alarming rate, and there were many "super communicators" who spread SARS to dozens or even dozens of people. In March 2003,The University of Hong Kong and the US Centers for Disease Control and Prevention have successively isolated a virus from SARS patients. Under the electron microscope, this virus looks like a crown of medieval European emperors. According to the morphological characteristics and genetic information, scientists believe that this new coronavirus is the pathogen of SARS, and it is a coronavirus that has never been found in humans. Later, researchers in China began to look for the source of the virus. They found that the earliest 11 cases had a history of contact with wild animals in Otawa. Following this clue, scientists first aimed at the Guangdong wildlife market, and soon separated and detected the virus exactly the same as SARS virus in the civets in the market. After this discovery was announced, Guangdong Province issued a ban in early 2004: completely killing civet cats in the wild animal market, banning wildlife trade and closing the wild animal market. However, Shi Zhengli and her team are not satisfied. For this new virus, we must find the source, that is, the "natural host"-an animal that carries a virus for a long time, but it does not get sick itself and can live in peace with the virus. Because the Hendra virus that broke out in Australia in the 1990s and the Nipah virus that broke out in Malaysia were later confirmed to be fruit bats, Shi Zhengli and her team focused their attention on bats. In 2004, the team collected fruit bats from Guangdong and Guangxi for the first time, and tested the genetic material in the laboratory. As a result, nothing was found after 8 months. Later,Antibodies to SARS virus were found in three species of bats in Guangxi and Hubei, and they followed suit, and coronavirus was detected in these three species of bats. In 2005, Shi Zhengli and her team published their research results in the journal Science. However, after careful comparison, it is found that there are still some differences between bat SARS-like coronavirus and SARS virus found in 2005, especially the most critical gene that determines the infectivity and pathogenicity of the virus is not the same. Later, they continued to search all over the country, whether in the south or the north, in the middle or in the west, whenever they heard that there were bats, they would go all over 28 provinces and cities in China, just like looking for a needle in a haystack. In 2011, Shi Zhengli and her team isolated and detected a highly homologous SARS-like coronavirus in a cave in Yunnan. Apart from the close evolutionary relationship, they are also very similar in function.

  They monitored the cave for five years, sampling twice a year, and found more than ten different types of SARS-like coronavirus. Although no virus exactly the same as SARS virus was found, a natural gene pool of SARS virus was found.

  After 13 years of tracking, they finally determined the bat origin of SARS virus. In January 2019, the project "Research on Bats Carrying Important Viruses in China" led by Shi Zhengli won the second prize of the National Natural Science Award in 2018. On January 29th, American Academy of Microbiology announced the list of Fellows of American Academy of Microbiology in 2019, and Shi Zhengli was elected. The American Academy of Microbiology is one of the subsidiaries of the American Society for Microbiology, the world’s largest and oldest member organization in the field of life sciences, and it is in the leading position in the international microbiology discipline. Among the scientists elected as Fellows, there are many Nobel Prize, Lasker Prize and national medal of science award Prize winners. Mysterious P4 Laboratory At the beginning of 2003, the spread of SARS in China virtually gave birth to the construction of the first P4 laboratory in China, and this important task fell on the shoulders of Wuhan virus, which is in an important transition period. In February 2003, Hu Zhihong, then director of Wuhan Institute of Virology, Chinese Academy of Sciences, suddenly received a phone call from Chen Zhu, then vice president of Chinese Academy of Sciences, asking if he could undertake the task of building P4 laboratory in Wuhan. Hu Zhihong immediately said that he would go all out. Hu Zhihong immediately called the party and government leading bodies of the Institute to discuss, and decided that Yuan Zhiming, then deputy director, was responsible for the preparation of P4 laboratory. At the same time, he ordered Yuan Zhiming, a visiting scholar at the University of Illinois in the United States, to end his trip and immediately return to China to prepare for P4 laboratory construction. On March 25th, 2003, Wuhan Institute of Virology submitted to the Biological Bureau of Chinese Academy of Sciences.Report on "Request for Instructions on Establishing P3 and P4 Laboratories". P4 laboratory is based on the degree of harm and protection required to deal with pathogenic microorganisms in the world. In the world, biosafety laboratories are usually divided into four levels, with the first level of protection being the lowest and the fourth level of protection being the highest. In the highest-level biosafety laboratory, in addition to other general protective measures, positive pressure protective clothing, airtight doors, chemical showers, sewage treatment systems, air filtration systems, etc. are specially set up to avoid the threat of operated harmful biological factors through protective barriers and management measures. Due to the complexity of construction and maintenance and high technical requirements, China has no experience in building P4 laboratory and maintenance, and needs to seek international cooperation to carry out laboratory construction. From April 5 to 11, 2003, Yuan Zhiming went to France with Chen Zhu to seek cooperation in P4 laboratory construction and research on emerging diseases. After consultation with Ms. Haignere, French Minister of Research and New Technology, she reached a preliminary cooperation intention. Chen Zhu and Yuan Zhiming saw P4 laboratory for the first time in Lyon, and its glass shell was colorful at night. After visiting it, they found that the internal structure and technology were particularly complicated. The P4 laboratory in Lyon was designed and built by French company Meria and RTV. During the visit, Wang Shaoqi, then Minister Counselor of the Chinese Embassy in France, discussed the Sino-French cooperation with Chen Zhu and Yuan Zhiming. That night, Wang Shaoqi asked Yuan Zhiming to stay in the confidential room of the embassy, wrote an internal report of nearly ten thousand words and sent it back to China.The contents are as follows: The research of infectious diseases in France has been highly valued by the government, and the first level-4 biosafety laboratory in Europe has been established in Lyon, and the Pasteur Institute is also the earliest unit in the world to carry out SARS research. To carry out the research on emerging diseases, P3 and P4 laboratories with high biosafety level should be established first, so as to prevent infectious pathogens from being released into the environment, and at the same time provide researchers with high biosafety guarantee. Some P3 laboratories have been established in China to carry out some research on SARS pathogens, but the research on some more virulent infectious pathogens and possible new disease pathogens must be carried out in P4 laboratory with the highest security level. Therefore, the establishment of P4 laboratory will become an important technical platform and guarantee for China to carry out research in related fields. On January 28th, 2004, when president Hu Jintao visited France, he witnessed the signing of the Memorandum of Understanding on Sino-French Cooperation on Preventing and Combating Emerging Infectious Diseases between the Government of People’s Republic of China (PRC) and the Government of the French Republic: the establishment of a Sino-French emerging infectious disease group composed of representatives and experts from the competent French government departments; Support the development of Wuhan Institute of Virology, Chinese Academy of Sciences, acquire the necessary equipment and technology for establishing a high-level biosafety laboratory, and provide relevant support and training. On November 26th, 2007, when French President Nicolas Sarkozy visited China, China and France signed a supplementary statement on the cooperation agreement on the prevention and control of emerging infectious diseases, emphasizing "to ensure that all necessary measures are taken as soon as possible to implement all planned projects including Wuhan P4 laboratory".. In 2008, France delivered a laboratory drawing, and in 2009, Zhongyuan Design Institute of China provided the drawings designed by China. In the design process, we refer to the main concepts of Lyon laboratory design to ensure the highest degree of safety. On January 9, 2012, the key equipment of the core laboratory-airtight door and life support system arrived in Jiangxia Zhengdian Park and passed the acceptance test. On January 31st, 2015, Wuhan P4 Laboratory held a completion unveiling ceremony, which marked the completion of hardware construction and installation of major facilities and equipment.

  The core area of Wuhan P4 laboratory is about 300 square meters, and it adopts the structure of "box in box". The interior of the laboratory is a negative pressure space, that is, the pressure inside is less than that outside, and air can only enter but not exit. The inside of this "big box" is divided into different areas by heavy metal doors, including cell laboratory, animal laboratory and animal autopsy room.

  Academician Gao Fu, director of China Center for Disease Control and Prevention, said: The official operation of Wuhan P4 Laboratory marks that China’s research on pathogenic microorganisms and immunology has entered the international advanced ranks, showing that China’s national security is another "frigate", which is comparable to the strategic deployment of China’s "two bombs and one satellite" in China. previous chapter

  The Truth Behind the "Squeezing Water" of Provincial Economic Data

This article first appeared on WeChat WeChat official account: See Finance. The content of the article belongs to the author’s personal opinion and does not represent Hexun.com’s position. Investors should operate accordingly, at their own risk.

(Editor: Zhang Yang HN080)

Hard-core data witness the strong pulse of development "multi-point flowering" to boost China’s sustained economic recovery

CCTV News:According to the data released by the National Energy Administration on May 17th, in April, the electricity consumption of the whole society was 741.2 billion kWh, a year-on-year increase of 7.0%.

Among them, the electricity consumption of the primary industry was 9.6 billion kWh, a year-on-year increase of 10.5%; The electricity consumption of the secondary industry was 517.1 billion kWh, a year-on-year increase of 6.2%; The electricity consumption of the tertiary industry was 127 billion kWh, a year-on-year increase of 10.8%; The domestic electricity consumption of urban and rural residents was 87.5 billion kWh, a year-on-year increase of 5.9%. 1— In April, the electricity consumption of the whole society totaled 3,077.2 billion kWh, up 9.0% year-on-year.

State Administration of Foreign Exchange: China’s cross-border capital flow is more balanced

According to the latest data from the State Administration of Foreign Exchange, in April, banks settled 173.7 billion US dollars and sold 211.8 billion US dollars. In April, the bank’s foreign-related income on behalf of customers was US$ 592.1 billion, and foreign payments were US$ 630.3 billion.

General Administration of Market Supervision: Strengthening the Supply of Regional Collaborative Standards and Promoting Integrated Development

The relevant person in charge of the General Administration of Market Supervision introduced on May 17 that standards are an important bridge and link to promote interconnection, and have an important "soft connectivity" role in promoting regional coordinated development and building a unified national market. The General Administration of Market Supervision will incorporate the demand for regional collaborative standards into the construction of the national standard system and strengthen the supply of regional collaborative standards.

According to reports, the General Administration of Market Supervision issued the "Guidelines for the Standardization of Major Strategies in Serving Countries and Regions", which has promoted the establishment of standardization coordination mechanisms in five regions. Up to now, Beijing-Tianjin-Hebei has issued 86 local standards for regional coordination, involving transportation, ecological environment and other fields. The Yangtze River Delta has formulated 36 local standards for regional coordination in the fields of digital government and transportation. Guangdong-Hong Kong-Macao Greater Bay Area announced 183 "Bay Area Standards". The Shuangcheng Economic Circle in Chengdu-Chongqing area has issued nine regional collaborative local standards around the fields of smart transportation and big data application.

Liu Chengyang, deputy director of the Standard Innovation Management Department of the State Administration of Markets, said: "Promoting the construction of regional coordination standards is conducive to breaking administrative barriers, supporting policy coordination, and promoting regional integration to a deeper level."

Ministry of Transport: Transportation work has basically achieved "standards to follow"

The relevant person in charge of the Ministry of Transport introduced on May 17th that since the "14th Five-Year Plan", the Ministry of Transport has continuously strengthened the top-level design of standards, actively created a standard system suitable for accelerating the construction of a transportation power, and basically achieved "standards to follow" in all work.

According to statistics, by the end of 2023, there were 908 effective national standards, 3,145 industry standards and 2,405 local standards in transportation, which basically achieved "standards to follow" and laid a solid standard foundation for accelerating the construction of a transportation power.

In terms of supporting the construction of comprehensive three-dimensional transportation network, a series of comprehensive transportation standards have been formulated and issued, which have supported the construction of 25 hub cities and more than 300 freight hub projects nationwide, and promoted the long-distance transportation of bulk goods and containers, as well as the development of iron-water combined transport and river-sea combined transport. In addition, the construction of the standard system has played an important role in promoting the upgrading of transportation equipment, helping the development of smart transportation and building the bottom line of traffic safety.

Xu Wenqiang, director of the Science and Technology Department of the Ministry of Transport, said: "The series of mandatory standards for road traffic signs and markings have been applied to highways and urban roads for more than 5.35 million kilometers, and passed the ‘ Traffic language ’ The standardization of setting guides and regulates road users to use roads in an orderly manner, which improves the overall operating efficiency of the road network and ensures public safety and orderly travel. "

Civil Aviation Administration of China: Promoting the further resumption of international passenger flights

At the press conference held on May 17th, the Civil Aviation Administration of China stated that it would continue to focus on increasing the number of international passenger flights this year and make every effort to further resume international passenger flights.

According to the data of the Civil Aviation Administration of China, from May 6 to May 12, the Chinese and foreign aviation companies carried out a total of 5,493 scheduled international passenger flights (each round-trip flight is counted as one flight), recovering to about 73.1% in 2019, and passenger flights were opened to 70 countries.

Air China has opened to Beijing, Cuba since May 17th — Madrid — Havana route, twice a week; HNA plans to open to Shenzhen, Hungary from June 21st — Budapest route, twice a week; China Southern Airlines plans to open to Guangzhou, Hungary from June 27th — Budapest route, 4 times a week.

Qing Xu, deputy director of the Transportation Department of the Civil Aviation Administration of China, said that the Civil Aviation Administration will continue to do a good job in the examination, approval and guarantee of flights on international routes, coordinate and solve the problems and difficulties encountered by airlines in the process of resuming international flights in a timely manner, and enhance the accessibility and convenience of international air transport.

The control of persistent organic pollutants in China has achieved remarkable results.

This year marks the 20th anniversary of the international entry into force of the Stockholm Convention on Persistent Organic Pollutants. On May 17th, the Ministry of Ecology and Environment issued "Control of Persistent Organic Pollutants in China (2004— 2024), which fully demonstrated the achievements and experience of China in the past 20 years.

The relevant person in charge of the Ministry of Ecology and Environment said that through unremitting efforts, China has embarked on a road of persistent organic pollutants control that conforms to China’s national conditions and achieved remarkable results. 29 kinds of persistent organic pollutants were successfully eliminated, and hundreds of thousands of tons of persistent organic pollutants and environmental emissions were avoided every year. Complete the two convention objectives of 100% off-line of PCB-containing power equipment in use and 100% environmentally sound disposal of waste PCB-containing power equipment ahead of schedule. With the output or disposal of dioxin-related industries increasing significantly, the emission intensity of dioxin in flue gas of key industries decreased significantly, and the total amount of dioxin discharged into the atmosphere gradually decreased after reaching its peak in 2012, and the concentration of dioxin in the atmospheric environment showed a corresponding downward trend.

Going to Chongqing to eat a few fly restaurants is the authentic taste hidden in the streets.

Chongqing beer and skittles WeChat official account news, what is a fly restaurant? Is it an edible fly?

No! No! No! Fly restaurant is a general term for all small restaurants in Chongqing.These restaurants are small in size and simple in facilities. Sanitary conditions are not very good.But they haveMysterious attraction and special tasteMake people want to stop.

In Chongqing, any place called food street is absolutely indispensable to a fly restaurant.

For Chongqing people, I haven’t eaten a few ugly or even "messy" fly restaurants hidden in small streets and corners, and I am embarrassed to say that I am a qualified foodie!

Several characteristics of fly restaurant

1. Fly restaurants are all over the streets, dense, like mosquitoes and flies scattered in the urban area..

A fly restaurant full of fireworksAlmost pervasive into the lives of Chongqing people..

Even near the bustling business districts, there will be several fly restaurants, which always attract Chongqing foodies.

2. Most of the shops in the fly restaurant are humble, and some are even more shabby.. You may have to take care of the sanitary conditions, and occasionally there are really one or two flies flying around.

It’s filthy, and it’s okay to eat it.The overbearing smell is always the reason why people flock to it.

There are too many delicious mouths in Chongqing, no matter how hidden the fly restaurant is, it can be like the "nose" of flies.Find those small shops deep in the alley with a keen sense of smell..

It is even said that most delicious dogs in Chongqing take it as fun to discover unique fly restaurants.

The delicious fly restaurant is very lively, people are talking and laughing, buzzing like flies, and the noise is endless.

The fly restaurant not only contains the delicious food in Chongqing, but also contains the truth of sincere human communication and life..

No matter what class you are, it won’t seem against you to enter the fly restaurant.. Both the boss driving an Audi BMW and the ordinary office worker riding a battery car can enjoy the most authentic Chongqing flavor in the low and dilapidated "semi-dangerous house".

Huangjie hotpot

The location of the old Chongqing hot pot is really off-center, and it is also quite "corner", but it still attracts countless diners to punch in, and there are long queues every day, 365 days a year.

You can directly call the driver to the door of the store by taking a taxi, but pay attention! Be sure to go early. It is common to start queuing at 4: 30. The special dishes, beef with pickled peppers and tender meat slices, are tender and refreshing after being cooked. The weight of each dish is not much, so you must like more! 

Per capita: 74 yuan

Address:163-1, Huangni Village, Wulidian Street/No.20, Rongjing Reach

(The two stores are not far away, so don’t miss them.)

Laoyuanzi pork intestines chicken

One of the hottest fly restaurants in Chongqing, at about 5 pm, the downstairs of the old yard was occupied by their small tables. Not only that, but there were also endless queues in the store.

However, its fat sausage chicken is really delicious: the marinated fat sausage is not rotten, and the more chewy it is, the more fragrant it is; Chicken is tender and slippery, and when you eat it in your mouth, it will automatically separate as soon as you sip it. It’s just that I heard that the price of fat sausage chicken has increased recently. The small pot is the price of the previous medium pot, and the medium pot is the price of the previous large pot. Qingmei is still a little sad after listening to it ~

Per capita: 54 yuan

Address: Xiaoyuan Community, Xiaoyuan Road, Jiangbei District (60 meters east of Chunhuiyuan Community Dry Cleaning Center)

Opposite the customs

In Chongqing, where there are many faces everywhere, the customs has always been quite satisfactory. It has been more than ten years since it started, but it has always been hidden in the vicinity of Guanyin Bridge.

Dry-distilled peas, dried noodles, beef noodles, Zhajiang Noodles, you can find everything you want here. Compared with ordinary Chongqing noodles, the taste is a little spicy. If you can’t eat spicy food, remember to ask your boss to put less sea pepper, or you can match a bowl of peach blossom soup. It’s still very good to relieve spicy food. 

Per capita: 15 yuan

Address: No.11, 41 Jianxin North Road, Jiangbei District

Dafo restaurant

Giant Buddha Restaurant, a Jianghu restaurant, has been open for more than 20 years, a veritable time-honored brand! Here, you don’t have to pay much attention to it. See the wall for the menu. Write your own menu and sit down.

The restaurant is run by a couple, one is responsible for cooking and the other is responsible for serving dishes and passing numbers. It is simple and simple, but here it is inexplicable. 

Per capita: 41 yuan

Address: at the foot of the Big Buddha Temple, Nanbin Road, Nan ‘an District

Datong ln wuming tofu pudding

When you don’t know what to eat, a bowl of tofu pudding rice can definitely solve all your problems. Even Bai Baihe put this store in Weibo when he filmed Passing Through Your World.

Tofu pudding is freshly ground every morning. It tastes delicate and melts in the mouth. A bowl of tofu pudding, a bowl of rice and a plate of dipping sauce can taste authentic Chongqing flavor at the civilian price in 8 yuan. 

Per capita: 25 yuan

Address: No.11 Datong Lane, Datong Road, Jie Fangbei

Yaoyao chicken

Like most great flies restaurants in Chongqing, its home looks shabby and unremarkable, but the things it makes are absolutely amazing! The store is not big, so you have to make a reservation in advance if you want to eat. There are a few onion segments floating on the thick red oil, and a spoon is scooped. The chicken in the big bowl is soft and glutinous, but it is not rotten and soft, and it is not stuffed with teeth. It is served with the store’s secret mustard tuber and dipped in a red oil dish. It is spicy and delicious. 

Per capita: 65 yuan

Address: No.87, Shengli Village, Tuwan

Wuming dish

Hanging nameless brand, the reputation is quite prominent. Braised pork intestines, minced garlic and white meat, and Maoxuewang are the must-have items in their home.

The traditional home-cooked taste, the weight of the food is also very sufficient, and the price is very cost-effective. The meat dishes are all around 20 or 30, and the per capita is about 30 pieces. 

Per capita: 32 yuan

Address: No.2, Zhongshan Third Road New Village (behind Hilton Hotel at Lianglukou)

Laodifang pettitoes soup

It is said that this store was opened in jiangbei town 33 years ago, and later moved to Longshan Road because of relocation. The shop opened by two old couples has a small storefront and few locations, and it is closed on weekends. The main course is hoof flower soup.

The hoof flower is stewed soft and rotten, easily capturing the stomach of the delicious mouth, and the chopsticks are rotten when they are sandwiched with meat, and they taste quite satisfactory. But to be honest, a 40-pound hoof flower is definitely expensive. 

Per capita: 47 yuan

Address: No.108 Songshi Branch Road, Attached to No.5 (near Longshan Middle School Bus Station)

Yuzhong hujia noodles

There is only a noodle restaurant with the size of Tintin ‘er in the storefront. Using the space at the entrance of the building and the cooperation of high and low benches, the classic Chongqing-style eating method is that one person is a table.

Zhajiang Noodles’s signature wide noodles are delicious with meat stuffing. The noodles are very strong and not too chewy. The spicy, delicious and fragrant noodles can all taste their own levels. 

Per capita: 12 yuan

Address: No.223 Renmin Road, Shangqing Temple

There are so many delicious flies in the restaurant, so hurry up and invite three or five friends to eat together!

Original title: Going to Chongqing to eat several fly restaurants is the original taste of Chongqing hidden in the streets.

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Frequent incidents of dog abuse experts and netizens call for speeding up animal protection legislation.

  Xinhua News Agency, Jinan, August 7th, New Media Specialist (Reporter Wang Yang, Zhang Yujie) Recently, dog abuse and killing incidents have been exposed in Weihai, Dongguan, Lianyungang and other places one after another. The related videos and pictures are cruel and savage, and both online and offline have aroused public dissatisfaction and heated discussion. Some netizens think that it is inappropriate to kill animals and be sentenced to damage property or undermine public security. Some netizens said that it is worrying that some people have no scruples about treating small animals.

  Frequent incidents of dog cruelty have aroused public anger, and what kind of punishment should be faced with such animal cruelty has aroused social discussion. The reporter interviewed relevant experts, lawyers and animal protection agencies on issues of concern to netizens.

  According to media reports, a citizen of Weihai, Shandong Province recently towed a pet dog with an off-road vehicle on the highway, causing some people to contain it. Related videos were circulated on the Internet.

  Coincidentally. According to netizens, a man living in Dongguan adopted more than 50 stray dogs and killed them for fun. According to a recent posting by a netizen in Lianyungang, a local woman was bitten by a big dog in a residential area when she came home with her boyfriend. Later, the woman’s boyfriend met the biting big dog again in the residential area and injured the dog. After that, the dog owner reported to the police that the dog had been killed.

  Lawyer Yang Shaogang, director of Shanghai Shaogang Law Firm, said that many recent incidents of dog abuse have aroused the indignation of the masses, but such cases are not individual cases, and some animal cruelty is more serious and cruel. For example: burning cats with fire, stepping on cats with high heels, beating dogs with sticks, and entertaining some mentally distorted people with various strange methods of cruelty to animals, but no cases of punishment have been seen. Because the law does not stipulate the punishment for cruelty to animals.

  Lawyer Yang Shaogang said that the incident in Shandong is slightly different from the general dog abuse. Because the owner of the car paraded through the street in front of the public, the people saw the animals being abused alive and died tragically, which caused compassion, so the onlookers and human flesh search were completely understandable. I think the public security organs can completely detain them for more than five days and less than ten days in accordance with Article 23 of the Law on Public Security Administration Punishment, and impose a fine of less than 500 yuan.

  The staff of China Small Animal Protection Association told the reporter that at present, China only has the Wildlife Protection Law of People’s Republic of China (PRC), but there is no relevant legislation for the protection of pets and domestic animals, which is not conducive to the protection of non-wild animals.

  The staff said that the recent incidents of cruelty to animals have had a very bad impact, which touched the bottom line of the people. However, without the protection of relevant laws, these abusers would only suffer moral condemnation at most, which is not enough to deter these abusers. They may also abuse animals again, hoping to introduce a comprehensive animal protection law as soon as possible.

  According to legal experts, there is no law against "cruelty to animals" in China except People’s Republic of China (PRC) Wildlife Protection Law, Regulations on the Management of Laboratory Animals, Regulations on the Management of Medical Laboratory Animals, Regulations on the Protection of Aquatic Wildlife and Regulations on the Protection of Terrestrial Animals. Article 29 of the Regulations on the Administration of Medical Laboratory Animals states: "The staff engaged in laboratory animals must take good care of them and shall not tease or abuse them." Article 31 stipulates: "According to the seriousness of the case, warning, improvement within a time limit or administrative sanctions shall be given respectively." This is for experimental animals, and there are no prohibitive regulations for general animals.

  Lawyers such as Yang Shaogang told reporters that since 2005, there have been many incidents of animal cruelty in China, and some people have called for legislation to protect animals. However, there are two different opinions, and the opposition to legislation has prevailed. Therefore, there has been no legislation on animal protection in China for a long time, but the legislation on wild animals has not only been enacted by the National People’s Congress, but also by many places. Its legislative purpose is not to consider animals as human friends, but as human resources, in order to prevent the loss or plunder of resources.

  According to incomplete statistics, more than 100 countries and regions have enacted the Law on the Prohibition of Cruelty to Animals, and the maximum penalty for cruelty to animals is imprisonment for less than five years. Britain, the United States, Japan, Italy, Germany, Canada and other countries have formulated the Animal Protection Law, the Animal Welfare Law and the Standards for Medical Laboratory Animals, which have made strict regulations on the protection of animals. Even if pets are lost, their owners will be punished, which shows that they attach importance to animal protection.

  Experts believe that the publication and publicity of animal cruelty, calling for everyone’s attention and condemnation, is itself the progress of animal protection awareness.

  Cao Han ‘ai, an expert in animal law at Griffith University in Australia, told the reporter, "Five or six years ago, I assisted legal scholars in drafting the Animal Protection Law of People’s Republic of China (PRC) (expert’s suggestion draft). At that time, the law against animal cruelty was too advanced in China and was not suitable for the national conditions at that time. But in recent years alone, China has made great progress, which is the progress of China society. "

  She introduced that at present, more and more animal activists and ordinary people in China, especially young people, have contributed their money to help all kinds of animals voluntarily, to condemn and stop abuses, to report illegal trafficking and hunting of wildlife under state protection, and so on. "All these show that people’s awareness of animal protection far exceeds the current legal provisions."

Fast food restaurants selling fruit fishing were claimed, and the court ruled that the informant’s profit was unjust and should be returned.

A fast food restaurant in Dongchangfu District, Liaocheng City, Shandong Province, cut fresh seasonal fruits into prepackaged ready-to-eat ingredients such as yogurt and canned red beans purchased through formal channels to make fruit fishing take-out, and the result was targeted. After the other party placed the order, it first reported that the fast food restaurant did not have a cold food production license, and then pointed out that the fruit fishing did not meet the food safety standards, and was awarded compensation to 1000 yuan.

Afterwards, the fast food restaurant sued each other and asked the court to decide to return 1000 yuan. Fast food restaurants believe that the other party is not an ordinary consumer, but a professional whistleblower, which is a disguised business behavior of making a purchase for the purpose of claiming compensation, and the 1000 yuan compensation it obtained is unjust enrichment.

On April 28, 2022, the Intermediate People’s Court of Binzhou City, Shandong Province announced the second-instance judgment of the dispute: the People’s Court of Wudi County, Shandong Province ruled that the defendant was unjustly enriched and should return 1000 yuan, a fast food restaurant, and pay interest on the occupation of funds. Binzhou Intermediate People’s Court upheld the original judgment in the second instance.

The fast food restaurant sold fruit fishing and was investigated and compensated 1000 yuan.

According to the court’s judgment, at about 15: 00 on August 11th, 2021, Yumou ordered an energy roll of runaway chicken breast and a fruit fishing with mango bursting beads from Youyou fast food restaurant in Dongchangfu District of Liaocheng City through the "Mei Tuan", with a total payment of 28.6 yuan, and Youyou fast food restaurant delivered it according to the contract. On the same day, Yumou reported that Youyou Fast Food Restaurant sold it "mango fried pearl fruit fishing" through the national 12315 platform, which was suspected of operating cold food beyond the permitted scope. After receiving the report, the market supervision office in front of Dongchangfu District Market Supervision Administration immediately inspected Youyou Fast Food Restaurant, told it not to operate cold food without obtaining the cold food license, and arranged the "Meituan" and "Hungry" platforms to stop the online operation of cold food in the store. At the same time, according to relevant regulations, it was decided to criticize and educate Youyou Fast Food Restaurant for its illegal behavior.

On August 17th, Yumou claimed 1000 yuan from the operator Guo on the grounds that the "mango and pearl-popping fruit fishing" he bought did not meet the food safety standards, and Guo transferred 1000 yuan to Yumou through WeChat.

Subsequently, Youyou fast food restaurant recovered the above money from Yu, but failed. Youyou Fast Food Restaurant brought a lawsuit to Wudi County People’s Court, requesting an order to return Youyou Fast Food Restaurant’s unjust enrichment of 1000 yuan, compensate for its occupation of 1000 yuan’s interest, and compensate for the loss of revenue from normal business projects brought to Youyou Fast Food Restaurant.

The focus of the dispute between the two sides: Is fruit fishing a food that does not meet safety standards?

Whether the fruit fishing involved meets the corresponding national food safety standards and food safety regulations has become the focus of controversy between the original defendant and the defendant.

Yu believes that the fact that Youyou Fast Food Restaurant has not obtained the license for the manufacture and sale of cold food, and the illegal manufacture and sale of food has been verified by Dongchangfu District Market Supervision Administration of Liaocheng City, and it can be confirmed that the food involved in Youyou Fast Food Restaurant’s operation does not meet the national food safety standards of GB14881-2013 and the relevant provisions of the General Rules for the Examination of Food Business License (Trial). At the same time, China’s Food Safety Law stipulates that the state implements a licensing system for food production and operation. Engaged in food production, food sales, catering services, shall obtain a license according to law. In the production of food that does not meet food safety standards, consumers can demand compensation from producers or operators for ten times the price or three times the loss, in addition to compensation for losses. According to the facts ascertained by the relevant administrative departments, Youyou fast food restaurant sells and sells cold food without obtaining the license of "selling and selling cold food", which violates the provisions of the Food Safety Law and causes certain security risks to a certain person. It should pay compensation of ten times the price to a certain person, and the increased compensation amount is calculated as 1,000 yuan if it is less than 1,000 yuan.

Youyou fast food restaurant obviously disagrees with the above opinion. Youyou fast food restaurant said that the fruit fishing produced and sold by the store is only prepackaged and cooked ready-to-eat vegetable ingredients such as big-brand yogurt, canned red beans, and fried eggs, which are cut fresh seasonal fruits and purchased through formal channels, and belong to plant cold food products. According to China’s Food Safety Law, food that does not meet the food safety standards refers to food that is toxic and harmful in essence, does not meet the proper nutritional standards, and may cause any acute, subacute or chronic harm to human health. The fruit fishing produced by Youyou fast food restaurant does not involve toxic and harmful substances, and it has due nutritional requirements and meets food safety standards. In addition, the business format of Youyou Fast Food Restaurant is an online shop, which only provides online catering services, and does not offer in-house meals. Its business premises are in line with the Code of Food Safety Operation for Catering Services. By listing the standards that are not applicable to the business format of online shops, it is inferred that the reason why the fruit fishing produced by Youyou Fast Food Restaurant does not meet the food safety standards cannot be established.

Youyou fast food restaurant also argues that Yu is a professional whistleblower, not an ordinary consumer, and the purchase of goods for the purpose of claiming compensation belongs to a disguised business behavior. Yu seriously violates the principle of good faith in order to achieve the purpose of earning profits by reporting rewards and should be resisted.

Court: No license does not necessarily violate food safety standards, and unjust enrichment should be returned.

The Wudi County People’s Court held in the first instance that based on the evidence submitted by a defendant, it can only prove that Youyou fast food restaurant has an illegal act of operating cold food without permission, but the food manufactured and sold without permission does not necessarily violate the food safety standards, and after a defendant clearly stated in the trial that he did not have diarrhea and other physical discomfort symptoms, so there is insufficient evidence that the food involved in a defense case does not meet the food safety standards, and he should bear the legal consequences of failing to prove it. Therefore, there is no legal basis for a profit, which constitutes unjust enrichment. Therefore, it is decided to return 1000 yuan, a Youyou fast food restaurant, and pay the interest on the funds occupied (based on 1000 yuan, the interest will be calculated at the annual rate of 3.85% from August 17, 2021 to the date of actual payment).

After the judgment of the first instance, Yu appealed.

The second instance of Binzhou Intermediate People’s Court held that the second paragraph of Article 148 of China’s Food Safety Law stipulates that consumers can demand compensation from producers or operators for ten times the price or three times the loss in addition to producing food that does not meet the food safety standards or operating food that they know does not meet the food safety standards; If the amount of additional compensation is less than 1,000 yuan, it will be 1,000 yuan. However, there are defects in the labels and instructions of food that do not affect food safety and will not mislead consumers. Article 150 stipulates that food safety means that food is non-toxic, harmless, meets the nutritional requirements and does not cause any acute, subacute or chronic harm to human health. Accordingly, the food that does not meet the food safety standards referred to in the second paragraph of Article 148 of the Food Safety Law shall refer to the food that is toxic and harmful in essence, does not meet the nutritional standards that should be met, and may cause any acute, subacute or chronic harm to human health.

In this case, Youyou Fast Food Restaurant did not obtain the cold food production license to produce and sell the products involved, but the products involved did not obtain the license to produce and sell did not mean that the products did not meet the food safety standards. The food production license and the food safety standards did not belong to the same category and could not be simply equated. Moreover, it was not proved that the cold food involved was toxic, harmful, did not meet the nutritional requirements, and had any acute, subacute or chronic harm to human health and other problems that affected food safety. Therefore, the basis for a claim for ten times compensation from Youyou fast food restaurant is not sufficient, and the judgment of the court of first instance is not improper.

On April 22, 2022, Binzhou Intermediate People’s Court ruled in the second instance that the appeal was dismissed and the original judgment was upheld.

It was reported that 11 restaurants sold cold dishes and sued State Administration for Market Regulation for rewards, which was rejected by the court.

The Paper inquired about China Judgment Document Network and found that there were more than 200 related judgment documents filed by Yu, many of which sued local market supervision departments for failing to get rewards for reporting.

A second-instance judgment of the Intermediate People’s Court of Dongying City, Shandong Province shows that in May 2020, Yu bought 11 cold dishes, including cold cucumber bean skin, preserved egg with ginger sauce, cold Flammulina velutipes, cold tomatoes, mixed bitter chrysanthemum, green onion mixed with tofu, mixed shredded potatoes, and baked tofu skin, from 11 restaurants through a US group takeaway, and then reported these 11 restaurants to the Dongying Hekou District Market Supervision Bureau. After receiving the report, Hekou Market Supervision Bureau warned the above-mentioned restaurants and ordered them to make corrections, but did not give a reward on the grounds that the report did not meet the reward conditions.

Subsequently, Yu sued the Hekou District Market Supervision Bureau to the court and asked for a reward for reporting. After trial, the court held that in this case, Yu’s above-mentioned behavioral characteristics reflected that his purchase behavior was not for consumption, and he did not submit evidence to prove that the quality of the products he bought damaged his legitimate rights and interests. In the end, it was determined that Yu did not meet the reward conditions in Article 6 of the Measures for Rewarding Reports of Food and Drug Violations, and the judgment rejected Yu’s prosecution.

According to a ruling of Tianjin Xiqing District Court on a lawsuit against Xiqing District Market Supervision Bureau for reporting reward, the court found that Yu had complained and reported 24 cases to Tianjin market supervision system since June 2020, demanding reporting reward. As of July 27, 2020, there were 204 lawsuits filed in a certain place, of which 39 were administrative litigation cases that refused to accept the decisions of market supervision and food and drug supervision. Most of the 165 cases are civil litigation cases in which disputes over sales contracts and online shopping contracts are prosecuted.

Xiqing District Court held that, in this case, the plaintiff filed a large number of complaints or filed lawsuits for rewards for the goods he bought in a short period of time, which obviously did not belong to ordinary consumers who bought goods or services for consumption, and his complaints and reports did not belong to acts implemented to safeguard their legitimate rights and interests. According to the spirit of Article 37 of the Opinions of the Central Committee of the Communist Party of China and the State Council on Deepening Reform and Strengthening Food Safety, malicious reporting of illegal profit-making is not a legal act protected by law, and its subject has no legitimate interests protected by law. In the end, the Xiqing District Court rejected Yu’s lawsuit in the first instance.

Enough blood! New Gods: Nezha Reborn deserves to be the first in the Spring Festival.

Special feature of 1905 film network When other Spring Festival movies are covered, it dares to be the first movie to be shown nationwide, and it may even be the last one.This behavior itself is very punk.It is an animated film featuring "Oriental Punk" (hereinafter referred to as "Nezha Rebirth").


Perhaps because of "Nezha" and the novel "Romance of Gods", this project has attracted much attention from the outside world since its initial exposure. In addition, the team of this animated film is the team that once detonated the market. When these elements are put together, they have already added value for it to become an explosion.

 

From the initial stage of exposure, the film has experienced many doubts, such as the heat, magic change … … All kinds of hats are buckled on its head. What many viewers actually don’t know is that as early as the beginning of 2016 — — Three years before the release of "White Snake: The Origin", the director had already started the creation of this film with the most senior animators, the light-chasing animation group.



Even if there were all kinds of voices outside, the team didn’t care. Just because of the force majeure of the epidemic, the film schedule was changed again and again, and finally the film was directly set in the most competitive Spring Festival file.

 

The various behaviors of the team also carry the "Nezha spirit".

 

"If Nezha is a modern man"


"White Snake: The Origin" has entered the post-production, so what should be done in the next work?

 

People including director Evonne have put forward their own ideas one after another, and "Nezha" has become the person with the highest repetition rate in the list of all people. At that time, the IP of "Nezha" was not popular. As a result, the light-chasing animation set up a team of "Nezha Rebirth" with Evonne as the core.

 


Nezha’s story is not easy to tell. I have seen it after 1980s and 1990s, and most of them grew up watching CCTV’s animated series "The Legend of Nezha" after 1990s. The audience of every era has their own stories about Nezha.

 

The whole team is almost born in the 1980s, so naturally they have a soft spot for What’s Making a Sea?


At the beginning, everyone intended to make a very traditional story and keep the original framework. However, Zhao Ji always feels that there is almost nothing. After all, being an antique, it will definitely not surpass the version of "What makes the sea" by the Film Studio.

 


Suddenly one day, he put forward a brand-new concept, "What if Nezha were a modern man?" From the team’s point of view, this idea is so cool that it can give people a chance to sit down and have a dialogue with the immortal character 3000 years ago.

 

This idea is very similar to "White Snake: The Origin", but the latter has not yet stepped onto the market to get feedback. This adaptation is somewhat risky for the team. Perhaps it is a willfulness. In short, Evonne doesn’t want to simply repeat the story, hoping to do something original. At this point, the embryonic form of The Rebirth of Nezha was formed.

 


In the movie, the masked man said to the man Li Yunxiang, "When I was a child, did your father put you on his lap and tell you the story of" What’s wrong with the sea? "

 

It seems that the other person is hinting at Nezha’s reincarnated identity, but in fact, this sentence is Evonne’s explanation of the origin of Nezha’s Rebirth.

 

"At that time, I wanted to" throw "White Snake."


With this idea, Evonne found Master Gui and asked him to try out a modern version of Nezha. The requirement was very clear. Don’t give Nezha the whole two drags, and then get him a motorcycle.

 

The whole thing was cool, and Mr. Turtle got high after listening to it. "Great, that’s ok."

 


Before Evonne found Master Gui, he and the producer decided to make the art of Nezha Rebirth into punk style. Punks’ unyielding and rebellious just fit the spirit of Nezha in their hearts.

 

This behavior is actually more risky than determining the idea of the story.

 

The average audience doesn’t know about punk, and even "punk" itself is a foreign word. Until later, because of the variety show "Summer of the Band", the general public began to be familiar with and understand what "punk" is.

 

But someone always needs to eat the first crab. Evonne and Master Gui decided to give it a try.

 


Later, they made a short film first, on the one hand, it was an exploration of style and technology, on the other hand, it was necessary to convince more people that punk was ok. "We feel that there should still be oriental elements in it, so as to bring the audience closer and convince them of the possibility of this fantastic idea."

 

After confirmation, Mr. Turtle, who is very punk in temperament, was excited. "I wanted to put White Snake: Origin aside and start Nezha Rebirth directly." At that time, he was troubled by the artistic modeling of Baoqingfang in White Snake: Origin.

 


Jokes are jokes, and Master Turtle finally handed over the high-quality White Snake: The Origin. Then, he began to write "Nezha Rebirth". At that time, he was more like the person who was reborn. His art scenes are very smooth, and even many scene styles are published in three versions. "There is nothing unsatisfactory, and each version has its own advantages. Finally, the director chooses according to the plot setting."

 

"Dragon Palace Office is the only regret"

 

When it comes to art design, Mr. Gui’s chatterbox is completely opened.

 

Punk emphasizes contradiction and conflict, and this concept is also embedded in the details of the scene. The city where the story happened is called Donghai City. The team spliced two kinds of urban landscapes, one is old Shanghai in the Republic of China, and the other is new york in the same period. The two forms the opposition between the East and the West, and at the same time creates a huge gap between the rich and the poor.

 

The main scene of the city actually corresponds to Shikumen in Shanghai. "When collecting wind, we saw those irregular and asymmetrical clothes poles and telephone poles, which made us feel particularly individual."


 

Besides, the Masked Man Warehouse and the Hanging Temple Hospital are the most satisfying scenes for Master Gui.

 

"The mask man gave me a particularly broad space to play. In our own words, it is a special character. He can integrate everything into his own environment. This state is especially in line with the art I have done. I can drag everything in and then do subtraction. The last thing that comes out makes me very happy. "

 

Scene map of masked man warehouse


With regard to the true identity of the masked man, Mr. Turtle put a lot of egg details in this scene, directly or indirectly, and even in one version, he gave instructions very clearly, but Evonne chose the more implicit plate type in the current version for plot consideration.

 

The masked man warehouse gave Master Gui a lot of freedom, while the Hanging Temple Hospital gave him a lot of whimsy.

 

"Don’t look at the Hanging Temple Hospital. It looks very mixed. In fact, I designed a set of architectural history for it and used a very complete system to tell why it changed from a temple to such a hospital." Mr. Gui once wanted to set up the hospital in the center of the city, but considering that the city was allocated by four families, he still chose to put this sacred place in the "three-no-care area" which has nothing to do with any rights and interests.

 


It seems that the whole process is very smooth, but the Dragon King’s office really stumped Master Gui. Although it doesn’t have too many visual elements, from an artist’s point of view, it is something worse after all. Evonne was not satisfied either, and the two men constantly overturned all kinds of plates until the current version was determined.

 


"Just for now, it has become my only regret for this movie." But after all, movies are an art of regret. If the Dragon Palace will appear again in the future, Mr. Turtle wants to readjust it.

 

"For the role performance style, please refer to Hot-blooded University"


When the first film "Rebirth of Nezha" was exposed overseas, it exploded on the Internet, which attracted not expectations, but all kinds of spit.

 

"Don’t talk about netizens, it’s embarrassing for us to watch it ourselves, but the audience who watched the whole film will know that it was an experiment and it didn’t appear in the feature film in the end." Mr. Turtle "started" his own work, and he was not at all polite.

 

Of course, at that time, the role design was the most criticized — — "The female host is like Alita" and "the male host is too like Wu Yifan". Even in the end, Wu Yifan, the stalk, did not even let the official himself go. The so-called official spit is the most deadly, which shows that this group of people really never play virtual.

 


Cui Yuemei, the role designer, did not shy away. "The Third Prince did refer to Wu Yifan’s performance. At that time, he looked like a gentleman in the park and had his own characteristics, so we made a reference."

 

In fact, every time she designs a role, she will look for many different references, such as reference to looks or reference to performance methods. The performance in "Hot-blooded University" is the object that Cui Yuemei has consulted the most.

 

Under this reference mode, many viewers’ greatest feelings after watching Nezha Rebirth are burning passion and blood.

 

All character designs are not simple. Li Yunxiang is the first character designed by Cui Yuemei in this work. She, Evonne and Master Gui have thought about many versions of modeling, and even in one version, Li Yunxiang is dressed in a Chinese tunic suit. After polishing over and over again, I finally got the present design.

 


When Li Yunxiang’s design is confirmed, the characters behind him will be much smoother. Of course, Cui Yuemei, who grew up watching "What a sea", also paid a lot of tribute to her role. "When I was a child, I was particularly impressed by the hag wearing a polka-dot skirt in the animation, so I came up with this idea when I decided on the role."

 


When it comes to "What’s Noisy about the Sea", we naturally think of such supporting characters as Xia Bing Xie. "We all designed them at the beginning, but in the end, we had to take them away because of the plot and other reasons." Cui Yuemei told us that there are actually "four killers" in the movies at first, including the soldiers and crabs.



"All the deleted plays have become subtitle eggs."

 

In fact, it’s not just these characters that have been deleted, but also many more exciting fighting scenes.

 

"When White Snake: The Origin, we cut 126 versions, and this time Nezha Rebirth will only be more." Editor Zhu Keer spent three years around "Nezha Rebirth", and the longest version, excluding the credits, lasted nearly 138 minutes.

 

This length of time is naturally not suitable for an animated film that wants to go on the market.

 


At the beginning, there was originally a racing scene with a man and Li Yunxiang. Considering that there was already a racing scene before, Zhu Keer and Evonne didn’t need to do it again, so delete it.

 

These adjustments are not a pity. When Li Yunxiang went to the Dragon King for the first time, there was actually a drama that was a mirror to the end, but it was finally deleted. "That scene was particularly handsome. We paid tribute to Uncle Face in Kingsman. He played a mirror to the end in the church." Between words, Zhu Keer has a lot of disappointment.


Evonne also loved the scene so much that he finally turned it into an egg and put it next to the film’s credits.

 


Before joining the light-chasing animation, Evonne had participated in many live-action movies, so this time when editing, he also proposed some editing methods that live-action movies prefer to appear.

 

At the beginning and end of the animation, Zhu Keer asked the protagonist to try to talk to the off-screen audience and try to break the fourth wall of the movie. "This way is not too much, one end is just right."



The editing work of Nezha Rebirth is actually a great breakthrough for her. As a cute girl, she has to face the rigid style of two men, Evonne and Gui Ye. "I often spit them out, and some things are really too’ straight’."


But it happened to be her presence that made this team a little more feminine.

 

Animated movies are different from live-action movies, and the editing department usually gets involved during the script. "In the earliest design, we cut out a very’ milk’ version of Li Yunxiang. Emotionally, he was a little biased towards his brother and sister, but in the end he considered his Nezha identity and maintained his current character. "

 


This time, the team is very restrained in emotional control, and the story orientation is very clear. The core is to do Li Yunxiang’s personal self-growth, not the love story like White Snake: The Origin. Although there are two female characters who seem to have emotional connection with Li Yunxiang in the film, there is no deeper emotional relationship in the end. As for whether there will be a story, "let the audience feel it for themselves."



So, how will the story after Nezha Rebirth develop? The egg at the end of the film has given the answer, and the next film will be about Yang Jian.


Mr. Gui assured us that he would be in charge of the whole series of fine arts and would have a very unified style. But as for what kind of plot it will be, he will not disclose more.


We joked that it is better to link up the first work of the light-chasing animation. After all, the goalkeeper was once a part of the story of "Feng Shen".

 

Guess is a guess, but at least from this Nezha Rebirth to the subsequent Yang Jian, the "New God List Series" of light-chasing animation is making a real animated film universe. This move may be even cooler than the movie!